Serviam in Caritate – Jackie and Zoey set out on an unexpected road trip. Stressed out by the long drive, Zoey finally confronts Jackie with her frustration. Meanwhile, Dr. Prince attracts a neighborhood mob to All Saints.
Coop Out – Jackie causes trouble as she rallies her fellow workers against the developers.
Flight – Season 6 ends with Akalitus ordering Jackie to take a drug test or admit that she’s using drugs. Meanwhile, Coop confronts Jackie, but she reveals to him a big surprise.
Sisterhood – Jackie heads to Kevin’s wedding, reluctantly. Zoey witnesses Jackie nearly make a fatal error with a patient, at work. Carrie wants to meet Coop’s mom. Akalitus feels pressured by the DEA.
Sidecars and Spermicide – Jackie and Frank breakup. Jackie realizes the only way she can continue to use drugs is by separating herself, from those closest to her. Carrie forgets Coop’s 40th birthday. Zoey decides that she wants to be a nurse practitioner. The DEA’s investigation continues.
Candyman – Jackie has to act quickly when she finds out she will have to provide a urine sample as part of a DEA investigation. Kevin and Mia begin making wedding plans. Coop and Carrie find a way of getting around their no sex in hospital rule.
The Lady with the Lamp – Jackie detoxes at home – with help. Frank raises an objection about Grace.
Rat on a Cheeto – Antoinette makes a harrowing confession when she confronts Jackie about her addiction and it has a sobering affect on Jackie. Later, Jackie comes to a crossroads when she finds drugs in Grace’s room. Meanwhile, Akalitus names Zoey nurse of the month; and Coop is named chief.
Nancy Wood – Jackie’s fake identity is compromised. Prentiss plans a date with Zoey.