Turkey Jerky – When George’s Mother invites him to Thanksgiving Dinner, George forces Doug and Doug’s dad to join them only to discover there might be sparks between George’s Mom and Doug’s Dad. Meanwhile, Dorothy spends Thanksgiving with Juanita’s family and Angela sets out to distract Yamamoto from calling his wife.
Ralphie – Dr. George Coleman and Dorothy Crane disagree on how best to deal with an overweight dog, “Ralphie,” and the over-indulging owner who is over-feeding him. George prefers threats and humiliation while Dorothy prefers a gentler approach. Meanwhile, Dorothy establishes a weekly “snack & chat,” which conflicts with the guys’ poker night.
Wingmen – George begins treating a cockatoo that keeps mysteriously ingesting chocolate, which can be fatal for the bird. While George tries to manage the eccentric owner, Sabrina French, Doug sets his sights on the socialite granddaughter, Tinsley French. Dorothy begins a movie night but when only Yamamoto shows up the two make the most of it and while Dorothy thinks it’s just casual, Yamamoto thinks otherwise! Meanwhile, Angela and Dr. Rizzo have to call the cable guy when their favorite legal program “Law of the Jungle,” is interrupted. Smitten with the cable guy’s take-charge manner, Angela schemes to get him back ASAP.
The Two George Colemans – George sees Jill as a threat to his standing at the hospital, so he tries to damage her reputation by sabotaging one of her operations. Meanwhile, Dorothy tries to remain impartial when she judges the facility’s annual Halloween contest for pet costumes.
Who’s Afraid of Virgina Coleman? – George must heal his demanding mother’s cat—or take its place as her constant companion. Meanwhile, Dorothy helps Dr. Leiter prepare for a meeting with the hospital’s board of directors.
Dr. Yamamazing – Dr. Yamamoto becomes a media sensation after saving the mayor’s dog in an emergency operation, though George isn’t buying into the hype. Meanwhile, Dorothy hires a capable new vet who is sure to test George’s mettle.
Clean-Smelling Pirate – George tries to console a boy whose Parson Russell Terrier was brought in with kidney failure, but Dorothy would prefer the infinitely more kid-friendly Doug take the case.
Pilot – When successful veterinarian Dr. George Coleman learns that his ex-girlfriend Dorothy Crane has inherited the hospital where he works and is now his boss, he is less than thrilled. George, who would rather spend time with his animal patients than with their human owners, is a stark contrast to the cheerful and optimistic Dorothy, who immediately inserts herself into the hospital business. As the sparks fly between George and Dorothy, the rest of the staff members struggle to maintain composure and do their jobs, including Dr. Doug Jackson, Dr. Yamamoto, Juanita, Nurse Angela and last but not least, “Dr. Rizzo,” the resident capuchin monkey at Crane Animal Hospital and George’s closest companion.